ECM skin booster · Cheongdam, Seoul

Re2O skin booster in Gangnam, Seoul

An ECM skin booster that replenishes the collagen and elastin framework of the skin itself — planned and injected personally by a MIN Clinic physician.

ECM skin booster 20–30 min 1–3 days mild bumps English-speaking team

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Quick answer

What is Re2O?

Re2O is a Korean extracellular matrix (ECM) skin booster made from micronized acellular human dermis (hADM). Rather than relying on a single active ingredient, it delivers collagen, elastin and glycosaminoglycans — the structural building blocks of healthy skin — to support elasticity, fine lines, texture and overall skin quality. Results build gradually over the weeks after treatment.

The dermis matrix is processed with the AlloClean method, without chemicals or surfactants, to preserve its 3D structure before micronization. The manufacturer describes the composition as roughly 89% collagen, 3% elastin, 0.4% GAGs including hyaluronic acid and 7.6% other ECM components.

On this page Treatment areas Before & after Your visit Compare FAQ

Treatment time: About 20–30 min
Numbing: Topical cream
Downtime: Mild bumps 1–3 days
Results visible: Gradually over weeks
Lasts: About 6–12 months
Sessions: Set at consultation
Performed by: MIN Clinic medical director
Location: Cheongdam, Gangnam

Treatment areas

What Re2O is used for

Injection depth and volume are adjusted for each zone of the face during a full-face treatment.

Reduced elasticity

Supports skin that feels thinner or less springy.

Fine lines

Softens crepey lines on the cheeks and around the eyes.

Uneven texture

Refines rough, tired-looking skin.

Enlarged pores

Improves the look of pores as skin quality improves.

A good fit if you…

want overall skin quality rather than added volume
have early elasticity loss or fine lines
have tried PN or PDLLA boosters and want a different approach
can avoid saunas and alcohol for about a week

Consider alternatives if you…

need structural volume — see dermal fillers
need a visible lift — see Ultherapy
are pregnant or breastfeeding
have active infection or inflammation in the area

Real patient result

Before & after Re2O

Drag the handle to compare. Photographed at MIN Clinic with the patient’s consent.

Treatment: Re2O ECM skin booster, full face
Concern: Skin quality, fine lines, texture
Downtime: Mild bumps 1–3 days
Clinic: MIN Clinic, Cheongdam-dong

Individual results vary. Photos are shown with patient consent and are not a guarantee of outcome. A doctor consultation is required before treatment.

View more before & after

How it differs

Re2O vs PN and PDLLA boosters

Each skin booster works by a different mechanism, which is why the right choice depends on your skin.

Re2O (ECM)

Supplies ECM components — collagen, elastin, GAGs — directly to the dermis.

Rejuran (PN)

Polynucleotides support repair and a calmer, healthier skin environment.

Juvelook (PDLLA)

Stimulates your own collagen gradually; good for pores and shallow scars.

Your plan

The doctor assesses thickness, laxity and texture before choosing.

Your visit

How your visit works

Most international guests complete the visit in one half-day, timed around their flight.

Consultation & analysis

The medical director assesses your skin and concerns and designs a full-face Re2O plan.

Numbing

Topical numbing cream is applied for comfort.

Injection

Re2O is injected at depths and volumes tailored to each area, in about 20–30 minutes.

Aftercare

Cleanse after 4 hours; avoid saunas, alcohol and intense exercise for about a week and use sunscreen.

Day 0 Right after

Small bumps (embossing), mild redness or swelling.

Days 1–3 Settling

Bumps and any bruising fade.

2–6 wks Building

Skin feels smoother and more resilient.

6–12 mo Maintain

Repeat sessions as advised to keep results.

Compare

Re2O vs other skin boosters

Your doctor may combine boosters depending on your goals.

Treatment	Key ingredient	Main action	Best for
Re2O	Micronized human dermis (ECM)	Replenishes skin matrix	Elasticity, fine lines
Rejuran Healer	Polynucleotides (PN)	Repair, calming	Sensitive, damaged skin
Juvelook	PDLLA + HA	Collagen stimulation	Pores, shallow scars
Olidia Myo	PLLA	Collagen stimulation	Firmness, thin skin

Medically reviewed by

Dr. Min Ji Kim

Director · Board-certified specialist, MIN Clinic Cheongdam

Former Director, Apgujeong ORACLE Dermatology
Member, Korean Society for Cosmetic Dermatology
Academic exchange, Shibuya Scramble Dermatology (miraDry), Japan

Reviewed by the MIN Clinic medical team Last updated: 12 October 2026

FAQ

Re2O questions we hear most

Can’t find your answer? Message our English-speaking team on WhatsApp.

How long does Re2O last?

Results typically last about 6 months to 1 year. The number of sessions and the interval between them depend on your skin and goals and are set at consultation.

Is Re2O painful?

Numbing cream is applied first, so most patients feel only brief pinpricks and pressure. The injection itself takes around 20–30 minutes.

What is the downtime after Re2O?

You can return to daily activities right away. Small bumps, mild redness, swelling or bruising can appear for 1–3 days; avoid saunas, alcohol and intense exercise for about a week.

Is Re2O better than Rejuran or Juvelook?

Not better, but different. Re2O supplies ECM components directly, Rejuran uses polynucleotides and Juvelook stimulates collagen with PDLLA. Your doctor recommends the one that fits your skin.

How much does Re2O cost in Seoul?

Pricing depends on the treatment area and number of sessions. Message MIN Clinic on WhatsApp for the current price, or see our event price list.

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